Gp78 E3 ubiquitin ligase mediates both basal and damage-induced mitophagy
Bharat Joshi, Yayha Mohammadzadeh, Guang Gao, Ivan R. Nabi
This study identifies Gp78 as an E3 ubiquitin ligase that mediates both basal and damage-induced mitophagy through distinct mechanisms involving mitochondrial homeostasis and PINK1.
bioRxiv · Sep 3, 2018 · PreprintCell Biology