Mechanical Memory Primes Cells for Confined Migration
Jia Wen Nicole Lee, Yeji Chang, Malhar S. Chitnis, Yixuan Li, Xu Gao, Avery Rui Sun, Jin Zhu, Jennifer L. Young, Andrew W. Holle
This study investigates mechanical memory in cells, showing that stiffness-sensitive cells improve confined migration after prior exposure to soft substrates, mediated by NFATC2.
Cell Reports · Apr 1, 2026Peer-reviewedCell Biology