Splanchnic-spinal transmission of gut-initiated α-synucleinopathy
Byung-Kwon Jung, Min Kyung Song, Yeongseo Kim, Dae Ki Hong, Myounghun You, Eun Hee Ahn, Seong Su Kang, Tae‐In Kam, Hyejin Park, Yoon‐Seong Kim, Greg S. B. Suh
This study shows that gut-initiated α-synucleinopathy spreads via the splanchnic-spinal pathway, not just the vagus nerve, and identifies spinal pathology in human Parkinson's disease.
bioRxiv · Oct 23, 2026 · PreprintNeuroscience