Author

Yi Kan Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ali BashashatiiD· 2 shared Sohrab P. ShahiD· 2 shared Tyler FunnelliD· 2 shared Adrian N. C. Wan· 1 shared Alex MirandaiD· 1 shared Alexandre Bouchard-Côté· 1 shared Allen W. ZhangiD· 1 shared Allen Zhang· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Ali BashashatiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Integrated single-nucleotide and structural variation signatures of DNA-repair deficient human cancers

Tyler Funnell, Allen Zhang, Yu-Jia Shiah, Diljot Grewal, Robert Lesurf, Steven McKinney, Ali Bashashati, Yi Kan Wang, Paul C. Boutros, Sohrab P. Shah

This study introduces a machine learning method to infer mutation signatures from both single nucleotide and structural variations in DNA repair deficient cancers, identifying new age-related and HRD-associated signatures in breast and ovarian cancers.

bioRxiv · Feb 18, 2018 · PreprintCancer Biology

The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer

Allen W. Zhang, Andrew McPherson, Katy Milne, David R. Kroeger, Phineas T. Hamilton, Alex Miranda, Tyler Funnell, Sonya Laan, Dawn R. Cochrane, Jamie L.P. Lim, Winnie Yang, Andrew Roth, Maia A. Smith, Camila de Souza, Julie Ho, , Sohrab P. Shah

The paper analyzes the interaction between tumor and immune clones in ovarian cancer, finding that immune contexture patterns mirror malignant spread and that foldback inversions correlate with poor outcomes.

bioRxiv · Oct 4, 2017 · PreprintCancer Biology