Katy Milne

This study engineers T cells to respond to G-CSF instead of IL-2, enabling effective melanoma treatment without lymphodepletion or IL-2.

This study shows that RORγ inverse agonism reduces tumor progression by altering myeloid cell organization and immune responses in gastroesophageal adenocarcinoma.

This study links circulating myeloid dysfunction, measured by cNLR, to tumour spatial organization in GEA through multiscale analyses of immune function, single-cell transcriptomics, and spatial myeloid organization.

The paper identifies self-reactive intra-epithelial plasma cells in ovarian cancer that correlate with improved prognosis and suggest a mechanism for immune response against tumor heterogeneity.

This study identifies four molecular subtypes of Hodgkin lymphoma using multimodal data, revealing distinct clinical features and immune ecosystem dynamics.

The paper uses single-cell sequencing to study the evolution of follicular lymphoma and its microenvironment during transformation, finding gene programs and TME changes associated with progression.

The paper analyzes the interaction between tumor and immune clones in ovarian cancer, finding that immune contexture patterns mirror malignant spread and that foldback inversions correlate with poor outcomes.