Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion
Pei Li, Yajie Liu, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yi-Min Zheng, Claire Carlin, Joseph S. Bednash, Jeffrey C. Horowitz, Rama K. Mallampalli, Linda J. Saif, Eugene M. Oltz, Daniel Jones, Jianrong Li, Richard J. Gumina, Shan-Lu Liu
This study compares immune evasion, antigenicity, and cell-cell fusion properties of SARS-CoV-2 BA.2.87.1 and JN.1 variants, finding BA.2.87.1 shows less neutralization escape and higher infectivity than JN.1 and XBB.1.5.
bioRxiv · Mar 11, 2024Microbiology