Uncoupling Drug and Microbiota Contributions to Chemotherapy-Induced Gut Toxicity
Hadar Bootz-Maoz, Sara Del Mare-Roumani, Gitali Naim, Ofir Azriel, Adva Cohen, Yifat Bennet, Efrat Sharon, Sivan Amidror, Nissan Yissachar
This study shows that both chemotherapy drugs and altered gut microbiota independently damage the intestinal barrier, but through different host transcriptional pathways.
bioRxiv · Jun 30, 2026 · PreprintMicrobiology