Author

Yifei Chen

Howard Hughes Medical Institute

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Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Angus McDonald· 1 shared Aravind SubramanianiD· 1 shared David A. AgardiD· 1 shared John W. Sedat· 1 shared Junrui LiiD· 1 shared Rajiv Narayan· 1 shared Shawn Q. ZhengiD· 1 shared Wooyoung Choi· 1 shared

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10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Angus McDonald

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2 papers

Recent·Most cited

Deconvolution improves cryo-EM maps

Junrui Li, Wooyoung Choi, Yifei Chen, Shawn Q. Zheng, Angus McDonald, John W. Sedat, David A. Agard, Yifan Cheng

This paper introduces a deconvolution method called AR-Decon to improve the quality of cryo-EM maps and shows it is robust and broadly applicable.

bioRxiv · Feb 23, 2025 · PreprintBiophysics

Gene expression inference with deep learning

Yifei Chen, Yi Li, Rajiv Narayan, Aravind Subramanian, Xiaohui Xie

This paper introduces a deep learning method to infer gene expression from landmark genes, showing significant improvements over linear regression in multiple datasets.

bioRxiv · Dec 15, 2015Bioinformatics