Author

Yifei Chen

University of California, San FranciscoORCID 0009-0005-8754-5779Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yifei Chen3 papers · Howard Hughes Medical Institute

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

James A. WellsiD· 2 shared Kevin LeungiD· 2 shared Trenton M. Peters-ClarkeiD· 2 shared Alex InagueiD· 1 shared Fangzhu ZhaoiD· 1 shared James A. OlzmanniD· 1 shared Johnathan C. MazaiD· 1 shared Kun MiaoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioengineering

James A. WellsORCID

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2 papers

Recent·Most cited

BioengineeringProceedings of the National Academy of SciencesPeer-reviewedSep 30, 2026

Targeted extracellular degradation of LRP8 promotes ferroptosis in cancer cells

Fangzhu Zhao, Alex Inague, Trenton M. Peters-Clarke…·James A. Wells

This study shows that targeting LRP8 for degradation reduces GPX4 levels, sensitizing cancer cells to ferroptosis by disrupting selenium-dependent antioxidant defenses.

1 citationtop 4%

humanexperimental assay

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Cancer BiologybioRxivPreprintJun 19, 2026

High-resolution photocatalytic crosslinking of protein neighborhoods using contact-dependent antibody mapping (contactMAP)

Johnathan C. Maza, Trenton M. Peters-Clarke, Yifei Chen…·James A. Wells

The paper introduces contactMAP, a photocatalytic crosslinking method for high-resolution mapping of protein neighborhoods, showing it rivals or outperforms existing photo-PLP methods.

1 citation

proteomicsexperimental assay

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