Author

John W. Sedat

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Angus McDonald· 2 shared Cornelis MurreiD· 1 shared David A. AgardiD· 1 shared Junrui LiiD· 1 shared Shawn Q. ZhengiD· 1 shared Wooyoung Choi· 1 shared Yifan ChengiD· 1 shared Yifei Chen· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Angus McDonald

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Deconvolution improves cryo-EM maps

Junrui Li, Wooyoung Choi, Yifei Chen, Shawn Q. Zheng, Angus McDonald, John W. Sedat, David A. Agard, Yifan Cheng

This paper introduces a deconvolution method called AR-Decon to improve the quality of cryo-EM maps and shows it is robust and broadly applicable.

bioRxiv · Feb 23, 2025 · PreprintBiophysics

Helical Coiled Nucleosome Chromosome Architectures during Cell Cycle Progression

Angus McDonald, Cornelis Murre, John W. Sedat

The paper describes helical coiled nucleosome chromosome architectures across the cell cycle, using cryo-EM data and computational modeling to show dynamic structural changes and replication processes.

Proceedings of the National Academy of Sciences · Oct 14, 2024Peer-reviewedCell Biology