Author

Yihan Pei

Wellcome/MRC Cambridge Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:clustering· 1

Frequent Co-Authors

Graziano MartelloiD· 2 shared Jennifer NicholsiD· 2 shared Sophie KraunsoeiD· 2 shared Takuya AzamiiD· 2 shared Thorsten BoroviakiD· 2 shared Kenneth Jones· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersDevelopmental Biology

Graziano MartelloORCID

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2 papers

Recent·Most cited

Requirement for STAT3 and its target, TFCP2L1 in self-renewal of naïve pluripotent stem cells in vivo and in vitro

Sophie Kraunsoe, Takuya Azami, Yihan Pei, Graziano Martello, Kenneth Jones, Thorsten Boroviak, Jennifer Nichols

The paper shows STAT3 and TFCP2L1 are essential for epiblast self-renewal during diapause, but only TFCP2L1 is needed for deriving embryonic stem cells in vitro.

Biology Open · Dec 12, 2022Peer-reviewedDevelopmental Biology

Distinct phospho-variants of STAT3 regulate naïve pluripotency and developmental pace in vivo

Takuya Azami, Sophie Kraunsoe, Graziano Martello, Yihan Pei, Thorsten Boroviak, Jennifer Nichols

This study shows that STAT3 phosphorylation variants regulate naïve pluripotency and developmental timing in mouse embryos, with loss of active STAT3 causing developmental delay and metabolic defects.

bioRxiv · Mar 8, 2022 · PreprintDevelopmental Biology