Author

Yikang Chen

Lanzhou Veterinary Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1

Frequent Co-Authors

Guiquan GuaniD· 1 shared Hong YiniD· 1 shared Hualin SuniD· 1 shared Jianhao Zhong· 1 shared Jianxun LuoiD· 1 shared Jifei YangiD· 1 shared Mengli WuiD· 1 shared Qingli NiuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Guiquan GuanORCID

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1 paper

Recent·Most cited

The African Swine Fever Virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses

Hualin Sun, Jifei Yang, Zhonghui Zhang, Mengli Wu, Zhancheng Tian, Ying Liu, Xiaoqiang Zhang, Jianhao Zhong, Songlin Yang, Yikang Chen, Jianxun Luo, Guiquan Guan, Hong Yin, Qingli Niu

This study identifies ASFV MGF_360-4L as a virulence gene that inhibits interferon signaling by degrading MDA5 via SQSTM1-mediated autophagy and blocking ISGylation, leading to reduced viral virulence in pigs.

mBio · Feb 25, 2025Peer-reviewedMicrobiology