Capture of mouse and human stem cells with features of formative pluripotency
Masaki Kinoshita, Michael Barber, William M. Mansfield, Yingzhi Cui, Daniel Spindlow, Giuliano Giuseppe Stirparo, Sabine Dietmann, Jennifer Nichols, Austin G Smith
The paper identifies and characterizes formative stem cells in mice and humans, showing they have unique transcriptional and epigenetic features compared to naive and primed pluripotent cells.
Cell stem cell · Dec 2, 2020Peer-reviewedDevelopmental Biology