Tissue Specific Requirement for the Inv(16) Oncogene CBFB::MYH11 in Acute Myeloid Leukemia
Sipra Panda, Yiqian Wang, Venkatasai Rahul Dogiparthi, Michelle E. Becker, Arjun Dhir, Calvin K. Lam, Cecilia Rivas, Lemlem Alemu, Lisa J Garrett, Peng Xiao, Samantha A. Swenson, Kyle J. Hewitt, R. Katherine Hyde
This study shows that CBFB::MYH11 is required for leukemia survival in spleen and peripheral blood but not in bone marrow, where it can be bypassed.
Oncogene · Aug 17, 2026Peer-reviewedCancer Biology