Computer-assisted dissection of the DNA mismatch recognition mechanism of the MutS protein
Wenyang Jiang, Yiyang Ding, Yuxuan Li, Haojie Sun, Xiao Huan Liang, Quanshun Li
The paper explains how TaqMutS recognizes DNA mismatches through a push-pull mechanism involving specific residues and electrostatic interactions.
bioRxiv · Dec 16, 2025 · PreprintSynthetic Biology