Author

Yiyi Zhang

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Bingrui ZhaoiD· 2 shared Huiqi XieiD· 2 shared Jiayu RuaniD· 2 shared Jie‐Min JiaiD· 2 shared Wentao Wang· 2 shared changzi Jiang· 1 shared Chunmeng SuniD· 1 shared Danping Lu· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Bingrui ZhaoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

AI-guided discovery of natural pocket proteins for portable small-molecule sensing

Liping Huang, Yihui Yang, changzi Jiang, Hongli Fan, Yuhong Li, Yiyi Zhang, Yuxue Zhang, Deyi Li, Hanlin Zhou, Youqian Chen, Wenjun Hu, Jianguo Guan, Xiangrong Liu, Chunmeng Sun, Gang L Liu

The paper develops an AI-guided workflow to identify natural pocket proteins for small-molecule sensing, achieving 43.8% binding response in tested pairs and demonstrating portable device performance with low serum LODs.

bioRxiv · Oct 23, 2026 · PreprintBioinformatics

Neurovascular Coupling in the Basolateral Amygdala Modulates Negative Emotions

Jiayu Ruan, Xinghua Quan, Huiqi Xie, Yiyi Zhang, Dongdong Zhang, Wentao Wang, Bingrui Zhao, Danping Lu, Yuxiao Niu, Mengyuan Diao, Wei Hu, Jie‐Min Jia

This study shows that neurovascular coupling in the basolateral amygdala bidirectionally modulates stress-induced negative emotions through manipulations in freely moving mice.

Cell Research · May 27, 2026Peer-reviewedNeuroscience

Ca2+ Oscillation in Vascular Smooth Muscle Cells Control Myogenic Spontaneous Vasomotion and Counteract Post-ischemic No-reflow

Jinze Li, Yiyi Zhang, Dongdong Zhang, Wentao Wang, Huiqi Xie, Jiayu Ruan, Yuxiao Jin, Tingbo Li, Xuzhao Li, Bingrui Zhao, Xiaoxuan Zhang, Jiayi Lin, Hongjun Shi, Jie‐Min Jia

This study identifies Ca2+ oscillations in vascular smooth muscle cells as critical for myogenic vasomotion and shows that restoring mitochondrial-ER contacts can improve reperfusion after ischemic stroke.

Communications Biology · Mar 15, 2024Peer-reviewedNeuroscience