Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling
Yoanna Ariosa-Morejon, Alberto Santos, Román Fischer, Simon A. Davis, Philip D. Charles, Rajesh V. Thakker, Angus K. T. Wann, Tonia L. Vincent
The paper uses in vivo pulsed SILAC to measure protein incorporation in mice tissues, finding reduced turnover and molecular changes linked to aging.
eLife · Sep 24, 2021Peer-reviewedDevelopmental Biology