Analysis of the high-order conformational changes in glyceraldehyde-3-phosphate dehydrogenase induced by nicotinamide adenine dinucleotide, adenosine triphosphate, and oxidants
Haruo Suzuki, Yuki Nicole Makiyama, Yuta Watanabe, Hideo Akutsu, Michiko Tajiri, Yoko Motoda, Ken‐ichi Akagi, Tsuyoshi Konuma, Satoko Akashi, Takahisa Ikegami
This study investigates how NAD+, ATP, and oxidants induce conformational changes in GAPDH, revealing structural instability and subunit splitting under specific conditions.
Biochemistry · Apr 21, 2025Peer-reviewedBiochemistry