Author

Takahisa Ikegami

Yokohama City UniversityORCID 0000-0002-1429-1844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Tsuyoshi KonumaiD· 2 shared Haruo SuzukiiD· 1 shared Hideo AkutsuiD· 1 shared Hiroaki SugaiD· 1 shared Ken‐ichi AkagiiD· 1 shared Michiko TajiriiD· 1 shared Satoko AkashiiD· 1 shared Tatsuya IkenoueiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Tsuyoshi KonumaORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 21, 2026

Fine-Tuning α-Synuclein Phase Separation through Sequence-Optimized Peptide Modulators

Tatsuya Ikenoue, Tsuyoshi Konuma, Takahisa Ikegami, Hiroaki Suga

This study develops a framework to design peptides that modulate α-synuclein phase separation by integrating deep mutational scanning and peptide screening.

DOI 10.64898/2026.02.21.707152

proteomicsdeep learning

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BiochemistryBiochemistryPeer-reviewedApr 21, 2025

Analysis of the high-order conformational changes in glyceraldehyde-3-phosphate dehydrogenase induced by nicotinamide adenine dinucleotide, adenosine triphosphate, and oxidants

Haruo Suzuki, Yuki Nicole Makiyama, Yuta Watanabe…·Takahisa Ikegami

This study investigates how NAD+, ATP, and oxidants induce conformational changes in GAPDH, revealing structural instability and subunit splitting under specific conditions.

4 citations

humanprotein structure

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