Analysis of the high-order conformational changes in glyceraldehyde-3-phosphate dehydrogenase induced by nicotinamide adenine dinucleotide, adenosine triphosphate, and oxidants
Haruo Suzuki, Yuki Nicole Makiyama, Yuta Watanabe…·Takahisa Ikegami
This study investigates how NAD+, ATP, and oxidants induce conformational changes in GAPDH, revealing structural instability and subunit splitting under specific conditions.