NeuroscienceACS Chemical BiologyPeer-reviewed
Analogs of the Dopamine Metabolite 5,6-Dihydroxyindole Bind Directly to and Activate the Nuclear Receptor Nurr1 (NR4A2)
Svetlana A. Kholodar, Geoffrey Lang, Wilian Augusto Cortopassi…·Pamela M. England
The paper identifies 5-chloroindole as a stable analog of DHI that activates Nurr1 and promotes dopamine-related gene transcription.
26 citations