A genome wide dosage suppressor network reveals genetic robustness and a novel mechanism for Huntington’s disease
Biranchi Patra, Yoshiko Kon, Gitanjali Yadav, Anthony Sevold, Jesse P Frumkin, Ravishankar R Vallabhajosyula, Arend Hintze, Bjørn Østman, Jory Schossau, Ashish Bhan, Bruz Marzolf, Jenna K Tamashiro, Amardeep Kaur, Nitin S Baliga, Elizabeth J Grayhack, , Animesh Ray
The paper identifies 660 novel suppressor interactions in budding yeast, revealing genetic robustness and a link between chromosome cohesion and Huntington's disease.
Nucleic Acids Research · Nov 29, 2016Peer-reviewedGenomics