Clonal dynamics of monozygotic twinning in early human embryogenesis
Sung-Soo Yoon, Chang Hyun Nam, Seung Mi Lee, Eun Saem Choi, Ji Hye Bae, Haemin Kim, Young Mi Jung, Joonoh Lim, Ryul Kim, Catherine A Derom, Eline Meireson, Steven Weyers, Jung Woo Park, Junehawk Lee, Joohon Sung, , Young Seok Ju
The paper uses post-zygotic mutations to analyze clonal dynamics in monozygotic twins and finds three clonal categories correlated with amnionicity, not chorionicity.
bioRxiv · Oct 5, 2025 · PreprintGenomics