Author

Ryul Kim

Korea Advanced Institute of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 4 Genetic & Genomic Medicine· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 5 Assay:whole-genome sequencing· 5 Research Focus:variant calling· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:variant effect prediction· 3 Approach:experimental assay· 2

Frequent Co-Authors

Young Seok JuiD· 6 shared Joonoh LimiD· 5 shared Kijong YiiD· 4 shared Seongyeol ParkiD· 3 shared Brian Baek-Lok Oh· 2 shared Chang Hyun NamiD· 2 shared Erin Connolly-Strong· 2 shared Hansol ParkiD· 2 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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6 shared papersGenomics

Young Seok JuORCID

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Clonal dynamics of monozygotic twinning in early human embryogenesis

Sung-Soo Yoon, Chang Hyun Nam, Seung Mi Lee, Eun Saem Choi, Ji Hye Bae, Haemin Kim, Young Mi Jung, Joonoh Lim, Ryul Kim, Catherine A Derom, Eline Meireson, Steven Weyers, Jung Woo Park, Junehawk Lee, Joohon Sung, , Young Seok Ju

The paper uses post-zygotic mutations to analyze clonal dynamics in monozygotic twins and finds three clonal categories correlated with amnionicity, not chorionicity.

bioRxiv · Oct 5, 2025 · PreprintGenomics

Target-enhanced whole-genome sequencing (TE-WGS) shows clinical validity equivalent to commercially available targeted oncology panel

Sangmoon Lee, Jin Roh, Jun Sung Park, İslam Oğuz Tuncay, Won‐Chul Lee, Jung‐Ah Kim, Brian Baek-Lok Oh, Jong-Yeon Shin, Jeong Seok Lee, Young Seok Ju, Ryul Kim, Seongyeol Park, Jaemo Koo, Hansol Park, Joonoh Lim, , Minsuk Kwon

This study compares target-enhanced whole-genome sequencing (TE-WGS) with a commercial targeted panel, showing TE-WGS detects all variants and provides additional clinical insights.

Cancer Research and Treatment · Sep 19, 2024Peer-reviewedGenetic & Genomic Medicine

Clinical application of whole-genome sequencing for precision oncology of solid tumors

Ryul Kim, Seokhwi Kim, Brian Baek-Lok Oh, Woo Sik Yu, Chang Woo Kim, Hoon Hur, Sang‐Yong Son, Min Jae Yang, Dae Sung Cho, Taeyang Ha, Subin Heo, Jeon Yeob Jang, Jae Sung Yun, Kyu‐Sung Kwack, Jai Keun Kim, , Minsuk Kwon

This study evaluates the clinical utility of whole-genome sequencing in solid tumors, showing 72% of reports provided clinically relevant insights and 69% aided therapeutic decision-making.

Experimental & Molecular Medicine · Aug 13, 2024Peer-reviewedGenetic & Genomic Medicine

Whole-genome sequences reveal zygotic composition in chimeric twins

Sung-Soo Yoon, Chang Hyun Nam, Taewoo Kim, Jeong Seok Lee, Ryul Kim, Kijong Yi, June‐Young Koh, Jiye Kim, Hyein Won, Ji Won Oh, Obi L. Griffith, Malachi Griffith, Joohon Sung, Tae Yeul Kim, Duck Cho, , Young Seok Ju

The paper uses whole-genome sequencing to determine zygotic composition in chimeric twins, finding asymmetrical contributions from two zygotes in blood but not in buccal tissues.

Human Genetics and Genomics Advances · May 20, 2024Peer-reviewedGenomics

Intravital imaging of cerebral microinfarct reveals an astrocyte reaction led to glial scar

Jingu Lee, Joon‐Goon Kim, Sujung Hong, Young Seo Kim, Soyeon Ahn, Ryul Kim, Heejung Chun, Ki Duk Park, Yong Jeong, Dong‐Eog Kim, Changjoon Justin Lee, Taeyun Ku, Pilhan Kim

The paper uses intravital imaging to study cellular changes after cerebral microinfarction in mice, finding that astrocyte reactivity leads to glial scar formation.

bioRxiv · Sep 29, 2021 · PreprintNeuroscience

Clonal dynamics in early human embryogenesis inferred from somatic mutation

Seongyeol Park, Nanda Maya Mali, Ryul Kim, Jeong‐Woo Choi, Junehawk Lee, Joonoh Lim, Jung Min Park, Jung Woo Park, Donghyun Kim, Taewoo Kim, Kijong Yi, June Hyug Choi, Seong Gyu Kwon, Joo Hee Hong, Jeonghwan Youk, , Young Seok Ju

This study uses somatic mutations to reconstruct cellular phylogenetic trees and analyze clonal dynamics in early human embryogenesis.

Nature · Aug 25, 2021Peer-reviewedGenomics

Mutational impact and signature of ionizing radiation

Jeonghwan Youk, Hyun Woo Kwon, Joonoh Lim, Eunji Kim, Ryul Kim, Seongyeol Park, Kijong Yi, Sara Jeon, Jinwook Choi, Hyelin Na, Eun-Seok Lee, Young-Won Cho, Dong‐Wook Min, Hyojin Kim, Yeong-Rok Kang, , Young Seok Ju

The paper investigates the mutational impact of ionizing radiation on normal cells and confirms these signatures in IR-induced cancers.

bioRxiv · Jan 12, 2021 · PreprintGenomics