NeurosciencebioRxivPreprint
Activation of hypoactive parvalbumin-positive fast-spiking interneuron restores dentate inhibition to prevent epileptiform activity in the mouse intrahippocampal kainate model of temporal lobe epilepsy
Sang-Hun Lee, Young‐Jin Kang, Bret N. Smith
This study investigates how parvalbumin-positive interneurons in the dentate gyrus change after status epilepticus and how their activity affects epileptiform activity in a mouse model of temporal lobe epilepsy.