Author

Yu Cheng

Charles University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Evolutionary Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:Arabidopsis· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Filip KolářiD· 2 shared Roswitha SchmickliD· 2 shared Alison Dawn ScottiD· 1 shared Anna GlushkevichiD· 1 shared Dejun YangiD· 1 shared Gabriela ŠrámkováiD· 1 shared Haowei CaoiD· 1 shared Jakub VlčekiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersEvolutionary Biology

Filip KolářORCID

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3 papers

Recent·Most cited

Structure-guided reinterpretation of a disease-associated CWH43 residue-533 truncation identifies internal disruption of a conserved C-terminal module in idiopathic normal pressure hydrocephalus

Haowei Cao, Zhihan Yan, Jing Wang, Yue Liu, Zheng Wei, Yu Cheng, Shuqun Hu, Dejun Yang

The paper reinterprets a CWH43 truncation variant in iNPH using structural analysis, showing it disrupts a conserved C-terminal module and cavity architecture.

bioRxiv · May 5, 2026 · PreprintGenetics

A Global Genomic Resource for Outcrossing Arabidopsis lyrata and Arabidopsis arenosa

Anna Glushkevich, Laura Steinmann, Nikita P. Tikhomirov, Jakub Vlček, Yu Cheng, Jana M. Flury, Uliana K. Kolesnikova, Miloš Duchoslav, Jörn Gerchen, Gabriela Šrámková, Roman Ufimov, Sonia Celestini, Saurabh Dilip Pophaly, Magdalena Bohutínská, Veronika Lipánová, , Polina Yu. Novikova

The paper presents a genomic resource with 1018 A. lyrata and 736 A. arenosa genomes, enabling studies of adaptation and genetic diversity through a searchable database and GWAS analysis of latitudinal clines.

bioRxiv · Mar 3, 2026 · PreprintEvolutionary Biology

How environment and genetic architecture of unreduced gametes shape the establishment of autopolyploids

Yu Cheng, Filip Kolář, Roswitha Schmickl, Josselin Clo

This paper challenges assumptions about polyploidy success by developing a theoretical model showing diploid adaptation, not tetraploid fixation, drives adaptation to new environments.

bioRxiv · Sep 13, 2024Evolutionary Biology