Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma
Tomoya Ueno, Shohei Otani, Yuki Date, Yu Katsuma, Yuma Nagayoshi, Tomoko Ito, Hiromi Ii, Susumu Kageyama, Susumu Nakata, Kosei Ito
The paper identifies GGCT as a Myc-target gene that promotes p53-deficient osteosarcoma development and suggests it as a potential therapeutic target.
Cancer Science · Jun 26, 2024Peer-reviewedCancer Biology