The Bacteriocin Sublancin Restores Vancomycin efficacy against vancomycin-resistant enterococci in vitro and in vivo
Xinyu Guo, Yuzhe Zhao, Chenglong Li, Yage Sun, Yuan fei Lu, Yanling Wang, Yangke LIU, Bing Ma, Xiang‐Dang Du, Dexi Li
This study shows that sublancin, a bacteriocin, enhances vancomycin's effectiveness against vancomycin-resistant enterococci in vitro and in vivo by down-regulating resistance genes.
bioRxiv · Feb 24, 2026 · PreprintPharmacology & Toxicology