Identification of Novel Extracellular Vesicles Scaffold Proteins for Versatile Cargo Engineering
Tao Qiu, Rui Hu, Yuan Yi, Wenqiang Lu, Chuang Cui, Shuiqin Niu, Ke Xu
This study identifies raftlin (RFTN1) and poliovirus receptor (PVR) as novel scaffold proteins for engineering extracellular vesicles to load lumen and surface cargos, showing efficient in vivo delivery.
bioRxiv · Jan 5, 2026 · PreprintBioengineering