Author

Yuanchao Hou

Shihezi University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jiaxin HuiD· 1 shared Miyesier Yusupujiang· 1 shared Shengwen YangiD· 1 shared Yixin Zhang· 1 shared You Xu· 1 shared Zhenming LiuiD· 1 shared Zhuoyan Liu· 1 shared Ziye LiuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Jiaxin HuORCID

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1 paper

Recent·Most cited

Pair-complete structural gating enables Pareto optimization of de novo cyclic peptides with preserved binding geometry and improved developability

Yuanchao Hou, Yixin Zhang, Zhuoyan Liu, 彭新发, Ziye Liu, Miyesier Yusupujiang, You Xu, Jiaxin Hu, Zhenming Liu, Shengwen Yang

This paper introduces RF-PepTune, a method that improves cyclic peptide design by preserving binding geometry while optimizing multiple properties, achieving higher success rates in structural and functional criteria.

bioRxiv · Sep 29, 2026 · PreprintBioinformatics