TMPRSS2 regulates ACE2 trafficking and shedding
Yue Qiu, Elena Popova, Oliver Popp, Philipp Mertins, Bernadette Nickl, Fatimunnisa Qadri, Michael Bader
This study investigates how TMPRSS2 affects ACE2 trafficking and shedding, showing that TMPRSS2 interaction alters ACE2 processing and glycosylation impacts these effects in vivo.
bioRxiv · Jun 18, 2026 · PreprintBiochemistry