Intestinal molecular siphoning by engineered bacterial spores for non-systemic treatment of nicotine addiction
Xisheng Xiong, Ruiqi Zhu, Yueqing Han, Mengxin Yu, Xuhui Xiang, Yulan Shao, Yijun Chen
This paper develops a live bacterial system to reduce nicotine levels in blood and brain by enzymatic degradation in the gut, showing potential for non-systemic treatment of nicotine addiction.
bioRxiv · Nov 4, 2026 · PreprintSystems Biology