A Premotor Excitation-Inhibition Motif Shapes Protopodium Dynamics During Drosophila Larval Forward Crawling
Ankura Sitaula, Lizzy Olsen, Dulanjana M. Perera, Yuhan Huang, Vashisht Errabolu Meher, Parinita Mitchelle Mandhyan, Nathan Byrd, Sara Arredondo, Lauren Carlisle, Yufeng Wan, Isuru S. Godage, Aref Arzan Zarin
In Drosophila larvae, ventral oblique (VO) muscles drive protopodium folding, and a tri-segmental A27h–A18b3–A06c premotor excitation-inhibition motif restricts their activation to a late, forward-specific window.
bioRxiv · Aug 22, 2026 · PreprintNeuroscience✦ In-depth digest