Yuhan Huang

In Drosophila larvae, ventral oblique (VO) muscles drive protopodium folding, and a tri-segmental A27h–A18b3–A06c premotor excitation-inhibition motif restricts their activation to a late, forward-specific window.

This study identifies the neuromuscular mechanisms underlying Drosophila larval rolling escape behavior, revealing circumferential muscle contractions and premotor circuitry involved in generating rolling motion.

The paper identifies premotor neuron microcircuits in Drosophila larvae that generate behavior-specific muscle activation patterns for forward and backward locomotion.