Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Using Cell-Free DNA 5-Hydroxymethylation Signatures
David Haan, Anna Bergamaschi, Gulfem Dilek Guler, Verena Friedl, Yuhong Ning, Roman E. Reggiardo, Michael Kesling, Micah Collins, Bill Gibb, Adriana Pitea, Kyle Hazen, Steve Bates, Michael Antoine, Carolina Fraire, Vanessa Lopez, , Samuel Levy
This paper validates a pancreatic cancer detection test using 5-hydroxymethylation signatures in cell-free DNA from patients with new-onset diabetes, showing high specificity and moderate sensitivity.
medRxiv · Dec 27, 2021 · PreprintGenetic & Genomic Medicine