NeurosciencePLoS GeneticsPeer-reviewed
Retrotransposon Activation Contributes to Neurodegeneration in a DrosophilaTDP-43 Model of ALS.
Lisa Krug, Nabanita Chatterjee, Rebeca Borges-Monroy…·Josh Dubnau
This paper shows that TDP-43 expression in Drosophila causes retrotransposon activation, leading to neurodegeneration through DNA damage and programmed cell death.
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