Transient receptor potential vanilloid channel 2 contributes to multi-modal endoplasmic reticulum and perinuclear space dilations that can also be observed in prion-infected mice
Wenda Zhao, Shehab Eid, Christopher Sackmann, Declan Williams, Xinzhu Wang, Yunqing Ouyang, Thomas Zerbes, Gerold Schmitt‐Ulms
The paper investigates ER and perinuclear space dilations in prion-infected mice and identifies TRPV2 as a contributor to this phenomenon, which may relate to spongiform degeneration.
Acta Neuropathologica · Jun 23, 2025Peer-reviewedNeuroscience