Author
University of Southern California
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Yuxiang Zhan, Binwei Yan, Ao Zhang, M Kellis, Na Sun
ProxiNet transfers spatially learned cellular proximity from spatial transcriptomics to dissociated single-cell transcriptomes, revealing tissue organization and age-related changes in Alzheimer's.
bioRxiv · Sep 30, 2026 · PreprintBioinformatics
Job Dekker, Betül Akgöl Oksuz, Yang Zhang, Ye Wang, Miriam K. Minsk, Shuzhen Kuang, Liyan Yang, Johan Harmen Gibcus, Nils Krietenstein, Oliver J. Rando, Jie Xu, Derek H. Janssens, Steven Henikoff, Alexander Kukalev, Andréa Willemin, , Feng Yue
The paper integrates 4D Nucleome data to analyze 3D genome structure and function in human cells, revealing chromatin domains, loops, and interactions, and showing how genetic variants affect genome folding.
Nature · Dec 17, 2025Peer-reviewedGenomics
Yuxiang Zhan, Francesco Musella, Frank Alber
This paper introduces MaxComp, an unsupervised method to predict single-cell chromatin compartments from 3D chromosome structures, showing that compartment annotations can be derived from geometric considerations alone.
PLoS Computational Biology · May 23, 2025Peer-reviewedBioinformatics
Yuxiang Zhan, Aslı Yıldırım, Lorenzo Boninsegna, Frank Alber
The paper introduces a dimensionality reduction method to classify single-cell chromosome structures into conformational clusters, revealing that distinct morphologies influence gene function through subnuclear positioning.
Genome biology · Feb 13, 2025Peer-reviewedGenomics