Author

Yuxuan Cai

Johns Hopkins University

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Molecular Biology· 1

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Approach:statistical model· 1

Frequent Co-Authors

Anthony K. L. LeungiD· 1 shared Charina S. FabilaneiD· 1 shared Haley E. TarboxiD· 1 shared Hongrui LiuiD· 1 shared Jamie B. SpangleriD· 1 shared Kun YueiD· 1 shared Leilei ShiiD· 1 shared Mark T. BedfordiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperMolecular Biology

Anthony K. L. LeungORCID

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1 paper

Recent·Most cited

Transient Poly(ADP-Ribose) Triggers FUS Condensation Hysteresis via a Prion-Like Mechanism

Hongrui Liu, Yuxuan Cai, Leilei Shi, Meenakshi Pillai, Nilimesh Das, Haley E. Tarbox, Yingda Ge, Kun Yue, Xingyi Yang, Piyush Rath, Mohsen Badiee, Charina S. Fabilane, Jamie B. Spangler, Mark T. Bedford, Sua Myong, , Anthony K. L. Leung

The paper shows PAR induces a conformational switch in FUS, enabling sustained condensation through N-terminal PrLD interactions after PAR degradation.

bioRxiv · Jul 3, 2025 · PreprintMolecular Biology