Author

Charina S. Fabilane

Johns Hopkins UniversityORCID 0000-0003-3801-7927Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Jamie B. SpangleriD· 2 shared Ananya K. MajumdariD· 1 shared Anthony K. L. LeungiD· 1 shared Claire H. WoodwardiD· 1 shared Daniel H. HwangiD· 1 shared Ella C. Teeley· 1 shared Gregory R. BowmaniD· 1 shared Haley E. TarboxiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Jamie B. SpanglerORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 3, 2025

Transient Poly(ADP-Ribose) Triggers FUS Condensation Hysteresis via a Prion-Like Mechanism

Hongrui Liu, Yuxuan Cai, Leilei Shi…·Anthony K. L. Leung

The paper shows PAR induces a conformational switch in FUS, enabling sustained condensation through N-terminal PrLD interactions after PAR degradation.

3 citations

statistical model

𝕏 PostBluesky

BiochemistryJournal of Molecular BiologyPeer-reviewedJan 1, 2024

Regulating IL-2 immune signaling function via a core allosteric structural network

Claire H. Woodward, Shahlo O. Solieva, Daniel H. Hwang…·Nikolaos G. Sgourakis

This paper investigates how dynamic structural networks in IL-2 superkines affect receptor binding and signaling, showing that modulating core dynamics can improve immune cell selectivity.

1 citation

humanprotein structure

𝕏 PostBluesky