Molecular BiologybioRxivPreprint
Transient Poly(ADP-Ribose) Triggers FUS Condensation Hysteresis via a Prion-Like Mechanism
Hongrui Liu, Yuxuan Cai, Leilei Shi…·Anthony K. L. Leung
The paper shows PAR induces a conformational switch in FUS, enabling sustained condensation through N-terminal PrLD interactions after PAR degradation.
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