BioengineeringbioRxiv
The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28
Y. Muller, D. Nguyen, L. M. R. Ferreira…·Q. Tang
This paper shows that CD28-TMD in CARs forms heterodimers with endogenous CD28, affecting T-cell responses and surface expression.
DOI 10.3389/fimmu.2021.639818