Focal adhesion membrane is dotted with protein islands and partitioned for molecular hop diffusion
T. K. Fujiwara, S. Takeuchi, Z. Kalay, Y. Nagai, T. A. Tsunoyama, T. Kalkbrenner, L. H. Chen, A. C. E. Shibata, K. Iwasawa, K. P. Ritchie, K. G. N. Suzuki, A. Kusumi
The paper demonstrates that focal adhesion membrane is partitioned into compartments where molecules undergo hop diffusion, with protein islands acting as dynamic hubs for integrin interactions.
bioRxiv · Oct 26, 2021 · PreprintCell Biology