KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury.
M. M. Al-bataineh, C. L. Kinlough, Z. Mi, E. K. Jackson, S. Mutchler, D. R. Emlet, J. A. Kellum, R. P. Hughey
The paper shows that MUC1 preserves KIM-1's anti-inflammatory activity during kidney injury by preventing its cleavage by ADAM17.
bioRxiv · May 20, 2021 · PreprintPathology