Author

Z. Michelini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Organism:non-human primate· 1

Frequent Co-Authors

A. Cara· 3 shared A. Giovannelli· 2 shared C. Chiozzini· 2 shared F. Ferrantelli· 2 shared F. Manfredi· 2 shared M. Federico· 2 shared M. Spada· 2 shared P. Leone· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

A. Cara

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Author profile →

3 papers

Recent·Most cited

Induction of SARS-CoV-2 N-specific CD8+ T cell immunity in lungs by engineered extracellular vesicles associates with strongly impaired viral replication

F. Manfredi, C. Chiozzini, F. Ferrantelli, P. Leone, k. Pugliese, M. Spada, A. Di Virgilio, A. Giovannelli, M. Valeri, A. Cara, Z. Michelini, M. Andreotti, M. Federico

This study shows that engineered extracellular vesicles inducing N-specific CD8+ T cells in lungs reduce SARS-CoV-2 replication in mice, with effects lasting up to three months post-vaccination.

bioRxiv · Jan 19, 2023 · PreprintImmunology

Strong SARS-CoV-2 N-specific CD8+ T immunity induced by engineered extracellular vesicles associates with protection from lethal infection in mice.

F. Ferrantelli, C. Chiozzini, F. Manfredi, P. Leone, M. Spada, A. DiVirgilio, A. Giovannelli, M. Sanchez, A. Cara, Z. Michelini, M. Federico

This paper shows engineered extracellular vesicles induce strong N-specific CD8+ T cell immunity in mice, which protects against lethal SARS-CoV-2 infection.

bioRxiv · Jan 10, 2022Microbiology

Persistent Immunogenicity of Integrase Defective Lentiviral Vectors delivering membrane tethered Native-Like HIV-1 Envelope Trimers

A. Gallinaro, M. F. Pirillo, Y. Aldon, S. Cecchetti, Z. Michelini, A. Tinari, M. Borghi, A. Canitano, P. F. McKay, R. Bona, M. F. Vescio, F. Grasso, M. Blasi, S. Baroncelli, G. Scarlatti, , A. Cara

This study shows that IDLV vectors with membrane-tethered native-like HIV-1 Env trimers induce faster and longer-lasting anti-Env IgG responses in mice and macaques, with some animals developing neutralization activity against HIV-1.

bioRxiv · Oct 8, 2021Immunology