Ligand-induced changes in dynamics mediate long-range allostery in the lac repressor
A. Glasgow, H. T. Hobbs, Z. R. Perry, S. Marqusee, T. Kortemme
This study uses HDX/MS to show ligand-induced changes in dynamics mediate long-range allostery in the lac repressor, revealing flexibility differences in secondary structures across functional states.
bioRxiv · Nov 30, 2021Biophysics