Multiplex spatial systems analysis of local nanodose drug responses predicts effective treatment combinations of immunotherapies and targeted agents in mammary carcinoma
Z. Tatarova, D. C. Blumberg, J. E. Korkola, L. M. Heiser, J. L. Muschler, P. J. Schedin, S. W. Ahn, G. B. Mills, L. M. Coussens, O. Jonas, J. W. Gray
The paper develops a MIMA system to assess drug combinations in tumors, identifying effective immunotherapy and targeted agent combinations with minimal toxicity.
bioRxiv · Sep 1, 2021 · PreprintCancer Biology