Author

J. E. Korkola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. W. Gray· 2 shared L. M. Heiser· 2 shared A. Basu· 1 shared A. D. Stern· 1 shared A. Demichele· 1 shared A. M. Barrette· 1 shared B. Gaudio· 1 shared B. Hu· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

J. W. Gray

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes

K. Yu, A. Basu, C. Yau, D. M. Wolf, H. Goodarzi, S. Bandyopadhyay, J. E. Korkola, G. L. Hirst, S. Asare, I-SPY 2 TRIAL, A. Demichele, N. Hylton, D. Yee, L. Esserman, L. van 't Veer, M. Sirota

This study uses computational drug repositioning to identify agents that can sensitize drug-resistant breast tumors, finding fulvestrant effective across multiple treatment and receptor subtypes.

bioRxiv · Mar 30, 2023Cell Biology

Multiplex spatial systems analysis of local nanodose drug responses predicts effective treatment combinations of immunotherapies and targeted agents in mammary carcinoma

Z. Tatarova, D. C. Blumberg, J. E. Korkola, L. M. Heiser, J. L. Muschler, P. J. Schedin, S. W. Ahn, G. B. Mills, L. M. Coussens, O. Jonas, J. W. Gray

The paper develops a MIMA system to assess drug combinations in tumors, identifying effective immunotherapy and targeted agent combinations with minimal toxicity.

bioRxiv · Sep 1, 2021 · PreprintCancer Biology

A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

M. Niepel, M. Hafner, C. Mills, K. Subramanian, E. H. Williams, M. Chung, B. Gaudio, A. M. Barrette, A. D. Stern, B. Hu, J. E. Korkola, LINCS Consortium, J. W. Gray, M. R. Birtwistle, L. M. Heiser, P. K. Sorger

This study investigates factors affecting the reproducibility of in vitro drug-response assays across multiple centers, identifying context-sensitive factors that impact results.

bioRxiv · Feb 5, 2019 · PreprintCancer Biology