Author

Z.-G. Han

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Q. Luo· 4 shared Y. Shi· 4 shared L. Wang· 3 shared X. Su· 3 shared G. Yang· 2 shared J. He· 2 shared J. Y. H. Yang· 2 shared K.-Y. He· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Q. Luo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Tumor subclones, where are you?

X. Su, S. Bai, G. Xie, Y. Shi, L. Zhao, G. Yang, F. Tian, K.-Y. He, L. Wang, X. Li, Q. Long, Z.-G. Han

This study compares bulk and single-cell mutational analysis to assess tumor clonal structure, finding that bulk analysis underestimates subclonal complexity and dynamic evolution.

bioRxiv · Jul 10, 2022 · PreprintCancer Biology

Designed peptides as potential fusion inhibitors against SARA-CoV-2 coronavirus infection

K. Chen, S. Bai, X. Zou, J. Hao, L.-t. Da, Z.-G. Han

The paper designs peptides based on SARS-CoV-2 spike protein HR1/HR2 domains to inhibit viral fusion and entry into host cells, showing they can form complexes with HR1 peptides.

bioRxiv · Jun 9, 2020 · PreprintMicrobiology

Single-cell dissection of a rare human prostate basal cell carcinoma

X. Su, Q. Long, J. Bo, Y. Shi, L.-N. Zhao, Y. Lin, Q. Luo, S. Ghazanfar, C. Zhang, Q. Liu, L. Wang, K.-Y. He, J. He, X.-F. Cui, J. Y. H. Yang, , G. Yang

This study characterizes the mutational and transcriptomic landscapes of a rare prostate basal cell carcinoma using single-cell sequencing, revealing unique gene expression and regulatory patterns.

bioRxiv · Oct 25, 2019 · PreprintCancer Biology

Single-Cell RNA-Seq Reveals Naïve B cells Associated with Better Prognosis of HCC

J. He, Y. Lin, X. Su, Q. Luo, S. Ghazanfar, J. Y. H. Yang, Z.-g. Han

This study uses single-cell RNA sequencing to identify naive B cells associated with better prognosis in human HCC by analyzing a mouse model and mapping to the TCGA database.

bioRxiv · Aug 12, 2019 · PreprintCancer Biology

ARID1a protects against steatosis and insulin resistance via PPARalpha-mediated fatty acid oxidation

y. qu, c. deng, q. luo, x. Shang, j. Wu, Y. Shi, L. Wang, Z.-G. Han

This study shows that Arid1a deficiency in mice leads to hepatic steatosis and insulin resistance by impairing fatty acid oxidation through PPARalpha.

bioRxiv · Jan 9, 2019 · PreprintCell Biology

The mutational features of aristolochic acid-induced mouse and human liver cancers

Z.-N. Lu, Q. Luo, L.-N. Zhao, Y. Shi, X.-B. Su, Z.-G. Han

This study investigates the mutational features of aristolochic acid-induced liver cancers in mice and humans, identifying characteristic A>T transversions and recurrent mutations in key cancer-related genes.

bioRxiv · Dec 28, 2018Cancer Biology