Author

Z.-Y. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Bin Yang· 1 shared C.-X. Zhao· 1 shared Deng WangiD· 1 shared Feng He· 1 shared H. Zhang· 1 shared H.-F. Wang· 1 shared H.-j. Liu· 1 shared Haitao WangiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperMolecular Biology

Bin Yang

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Author profile →

3 papers

Recent·Most cited

Peptide Information Compression Technology (PICT): A New Frontier in Therapeutic Peptide Discovery

Hong Wang, Zhu-Yin Wang, Wei-Ming Jiang, Qin-Qin Wang, Lin Miao, Deng Wang, Haitao Wang, Shiu-Feng Tung, Jin-Rui Yang, Bin Yang, Xu-Bo Liang, Z.-Y. Li, Xueping Wang, Sheng Zou, Feng He, , Xiang-Qun Li

This paper introduces PICT, a new technology for efficient therapeutic peptide discovery, and demonstrates its application in identifying active molecules with low nanomolar to micromolar potency.

bioRxiv · Dec 10, 2024 · PreprintMolecular Biology

Vitamin D promotes DNase1L3 to degrade ecDNA and inhibit the malignant progression of hepatocellular carcinoma

H. Zhang, L.-n. Qin, Q.-q. Li, T. Wu, L. Zhang, K.-w. Wang, S.-b. Cheng, Y. Shi, Y.-q. Feng, J.-x. Han, Y.-n. Li, Z.-y. Li, H.-j. Liu, T. Sun

This study shows vitamin D reduces ecDNA in hepatocellular carcinoma by stabilizing DNase1L3 via its transporter GC, leading to tumor suppression.

bioRxiv · Aug 30, 2023 · PreprintCancer Biology

Numerical Investigation of Drug Transport from Blood Vessels to Tumor Tissue Using a Tumor-Vasculature-on-a-Chip

W. Li, H.-F. Wang, Z.-Y. Li, T. Wang, C.-X. Zhao

This study uses a microfluidic Tumor-Vasculature-on-a-Chip model and numerical simulations to investigate how tumor size and positioning affect drug concentration distribution in the tumor microenvironment.

bioRxiv · May 28, 2019Bioengineering